Association of acetaminophen use with mortality and renal recovery in patients with sepsis-associated acute kidney injury

Long-Zhu Li, Lu-Ming Zhang, Yan Ye, Qing Su, Kan Fat Leong, Hai-Yan Yin, Wan-Jie Gu, Min Ma · 2024

Read Association of acetaminophen use with mortality and renal recovery in patients with sepsis-associated acute kidney injury by Long-Zhu Li, Lu-Ming Zhang, Yan Ye, Qing Su, Kan Fat Leong, Hai-Yan Yin, Wan-Jie Gu, Min Ma (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11603937.txt.

Description

Long-Zhu Li and co-authors studied whether acetaminophen use links to survival and kidney recovery in patients whose kidneys fail during sepsis, in a 2024 study. The drug is a common fever and pain treatment, but its ties to outcomes in this group were unclear. Their data came from a large critical care database.

Of 6,752 patients, 3,892 received the drug within seven days of kidney injury onset. Use of the drug tied to lower death rates at 28 days and in intensive care, with hazard ratios well under one. The authors also tracked deaths at later points and kidney recovery, using models that adjust for other factors.

Catalog record

CREATORLong-Zhu Li, Lu-Ming Zhang, Yan Ye, Qing Su, Kan Fat Leong, Hai-Yan Yin, Wan-Jie Gu, Min Ma
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE25 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11603937

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