Safety and efficacy of intralesional rituximab injection versus involved site radiation therapy in primary ocular adnexal MALT lymphoma: study protocol for a multicentre randomised controlled trial

Yaoming Liu, Yang Gao, Ling Jin, Qian Li, Xiaohui Wang, Yujie Wu, Jichao Zhou, Wei Liu, Lili Wang, Yuying Dong, Yajing Zheng, Lu Chen, Jinmiao Li, Shicai Su, Junjie Tang, Yinghao Wang, Weifeng Huang, Chao Cheng, Cheng Li, Ningyu An, Jia Tan, Hong Chen, Huiyu Guo, Yi Wang, Qing Zhou, Fei Han, Honglei · 2024

Read Safety and efficacy of intralesional rituximab injection versus involved site radiation therapy in primary ocular adnexal MALT lymphoma: study protocol for a multicentre randomised controlled trial by Yaoming Liu, Yang Gao, Ling Jin, Qian Li, Xiaohui Wang, Yujie Wu, Jichao Zhou, Wei Liu, Lili Wang, Yuying Dong, Yajing Zheng, Lu Chen, Jinmiao Li, Shicai Su, Junjie Tang, Yinghao Wang, Weifeng Huang, Chao Cheng, Cheng Li, Ningyu An, Jia Tan, Hong Chen, Huiyu Guo, Yi Wang, Qing Zhou, Fei Han, Honglei (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11603821.txt.

Description

Yaoming Liu and co-authors present a trial protocol, published in 2024, comparing two treatments for a slow growing eye lymphoma. The cancer, called MALT lymphoma of the ocular adnexa, sits around the eye and usually responds well to targeted radiation. Radiation controls the disease in most patients, yet side effects strike a sizable minority, sometimes harming the eye it aims to save.

The trial will run at eight eye centers in China and enroll about one hundred and eight patients. Assignment is at random, to radiation or to injections of the antibody drug rituximab straight into the tumor. Injections have shown high remission with few side effects in early reports. Complications over five years form the main measure, with response and survival tracked as well.

Catalog record

CREATORYaoming Liu, Yang Gao, Ling Jin, Qian Li, Xiaohui Wang, Yujie Wu, Jichao Zhou, Wei Liu, Lili Wang, Yuying Dong, Yajing Zheng, Lu Chen, Jinmiao Li, Shicai Su, Junjie Tang, Yinghao Wang, Weifeng Huang, Chao Cheng, Cheng Li, Ningyu An, Jia Tan, Hong Chen, Huiyu Guo, Yi Wang, Qing Zhou, Fei Han, Honglei
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11603821

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