Triage test for all-oral drug-resistant tuberculosis (DR-TB) regimen: a phase IV study to assess effectiveness, feasibility, acceptability and cost-effectiveness of the Xpert MTB/XDR assay for rapid triage and treatment of DR-TB
Kogieleum Naidoo, Anushka Naidoo, Alash'le G Abimiku, Everdina W Tiemersma, Agnes Gebhard, Sabine M Hermans, Derek J Sloan, Morten Ruhwald, Sophia B Georghiou, Evaezi Okpokoro, Aderonke Agbaje, Kalkidan Yae, Getachew Tollera, Shewki Moga, Hannelise Feyt, Takondwa Kachoka, Marothi P Letsoalo, Andrea · 2024
Read Triage test for all-oral drug-resistant tuberculosis (DR-TB) regimen: a phase IV study to assess effectiveness, feasibility, acceptability and cost-effectiveness of the Xpert MTB/XDR assay for rapid triage and treatment of DR-TB by Kogieleum Naidoo, Anushka Naidoo, Alash'le G Abimiku, Everdina W Tiemersma, Agnes Gebhard, Sabine M Hermans, Derek J Sloan, Morten Ruhwald, Sophia B Georghiou, Evaezi Okpokoro, Aderonke Agbaje, Kalkidan Yae, Getachew Tollera, Shewki Moga, Hannelise Feyt, Takondwa Kachoka, Marothi P Letsoalo, Andrea (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11603726.txt.
Description
Kogieleum Naidoo and co-authors lay out a large study of a fast sputum test to sort drug resistant tuberculosis care. Their protocol from 2024 covers sites in South Africa, Nigeria, and Ethiopia. The test, Xpert MTB/XDR, reads drug resistance from samples that test positive for the disease.
About 4,800 such patients will join over eighteen to twenty four months and be tracked for about six months after care ends. Groups split by resistance pattern: one with resistance to the main drug, and one with single drug resistance of a second kind. The study weighs how well the test works, how easy it is to run, how patients and staff receive it, and what it costs, to speed short all oral care.
Catalog record
| CREATOR | Kogieleum Naidoo, Anushka Naidoo, Alash'le G Abimiku, Everdina W Tiemersma, Agnes Gebhard, Sabine M Hermans, Derek J Sloan, Morten Ruhwald, Sophia B Georghiou, Evaezi Okpokoro, Aderonke Agbaje, Kalkidan Yae, Getachew Tollera, Shewki Moga, Hannelise Feyt, Takondwa Kachoka, Marothi P Letsoalo, Andrea |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |