Monitoring drug Efficacy through Multi-Omics Research initiative in Alzheimer’s Disease (MEMORI-AD): A protocol for a multisite exploratory prospective cohort study on the drug response-related clinical, genetic, microbial and metabolomic signatures in Filipino patients with Alzheimer’s disease
Fresthel Monica M Climacosa, Veeda Michelle M Anlacan, Francis James A Gordovez, John Carlo B Reyes, Ian Kim B Tabios, Rafael Vincent M Manalo, Joana Marie Ceripulo Cruz, Joannes Luke B Asis, Rozel B Razal, Mark Joseph M Abaca, Aira B Dacasin, Ayra Patrice N Espiritu, Nicole Clarence Louise L Gapaz, · 2024
Read Monitoring drug Efficacy through Multi-Omics Research initiative in Alzheimer’s Disease (MEMORI-AD): A protocol for a multisite exploratory prospective cohort study on the drug response-related clinical, genetic, microbial and metabolomic signatures in Filipino patients with Alzheimer’s disease by Fresthel Monica M Climacosa, Veeda Michelle M Anlacan, Francis James A Gordovez, John Carlo B Reyes, Ian Kim B Tabios, Rafael Vincent M Manalo, Joana Marie Ceripulo Cruz, Joannes Luke B Asis, Rozel B Razal, Mark Joseph M Abaca, Aira B Dacasin, Ayra Patrice N Espiritu, Nicole Clarence Louise L Gapaz, (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11603684.txt.
Description
Fresthel Monica Climacosa and a large team set out the plan for a study of how Filipino patients with Alzheimer's disease respond to standard memory drugs. No study has yet mapped drug response in this population. The plan joins clinic records with gene, gut germ, and body chemistry profiles across several sites.
At least one hundred fifty-three patients with mild or moderate disease, aged sixty-five and up, will be enrolled. A smaller group of sixty will be followed over time to link body signatures to drug response. The authors aim to learn why the same drug helps one patient and not another, guiding care tuned to Filipino patients.
Catalog record
| CREATOR | Fresthel Monica M Climacosa, Veeda Michelle M Anlacan, Francis James A Gordovez, John Carlo B Reyes, Ian Kim B Tabios, Rafael Vincent M Manalo, Joana Marie Ceripulo Cruz, Joannes Luke B Asis, Rozel B Razal, Mark Joseph M Abaca, Aira B Dacasin, Ayra Patrice N Espiritu, Nicole Clarence Louise L Gapaz, |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |