Effect of linex treatment on IFN-γ and IL-4 in mice infected with Trichinella

Shimaa Attia Atta, Zeinab H Fahmy, Eman AH Selim, Tarek Aboushousha, Reham Refaat Mostafa · 2024

Read Effect of linex treatment on IFN-γ and IL-4 in mice infected with Trichinella by Shimaa Attia Atta, Zeinab H Fahmy, Eman AH Selim, Tarek Aboushousha, Reham Refaat Mostafa (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11603642.txt.

Description

Shimaa Attia Atta and co-authors test, in a 2024 study, whether a common probiotic can help treat a worm infection in mice. Trichinella worms, caught from food, damage muscle. The probiotic, sold as Linex, was tried alone and alongside the standard drug albendazole.

The team tracked worm counts, immune signals, and tissue state in the gut and muscle stages. The combined treatment cut adult and larval counts the most, the authors report. It also shifted the immune response toward a protective pattern, raising one signal while rebalancing another. The study claims this pairing is the first of its kind for this infection. Probiotics as drug partners could matter where resistance or side effects limit standard care.

Catalog record

CREATORShimaa Attia Atta, Zeinab H Fahmy, Eman AH Selim, Tarek Aboushousha, Reham Refaat Mostafa
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11603642

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