High expression of malic enzyme 1 predicts adverse prognosis in patients with cytogenetically normal acute myeloid leukaemia and promotes leukaemogenesis through the IL-6/JAK2/STAT3 pathways

Chang Zhang, Wenlu Li, Fei Wu, Zhongwei Lu, Piaorong Zeng, Zeyu Luo, Yixiong Cao, Feng Wen, Junjun Li, Xi Chen, Fujue Wang · 2024

Read High expression of malic enzyme 1 predicts adverse prognosis in patients with cytogenetically normal acute myeloid leukaemia and promotes leukaemogenesis through the IL-6/JAK2/STAT3 pathways by Chang Zhang, Wenlu Li, Fei Wu, Zhongwei Lu, Piaorong Zeng, Zeyu Luo, Yixiong Cao, Feng Wen, Junjun Li, Xi Chen, Fujue Wang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11603458.txt.

Description

Chang Zhang and co-authors flag a fat-burn gene as a mark of ill fate in a 2024 study. The ill is a blood seed cancer whose gene maps read plain, so risk calls there rest on few marks.

In bank sets of the sick, high counts of the gene tied to short spans free of ill and short life. The tie held when all else was weighed. A risk score built on the gene split the sick in a high pack that fared worse by a wide odds mark. In dish cells, hush of the gene curbed growth of the cancer. Gene set reads tied the gene to a burn call path through the cell's growth switch. The authors cast the gene as both mark and aim.

Catalog record

CREATORChang Zhang, Wenlu Li, Fei Wu, Zhongwei Lu, Piaorong Zeng, Zeyu Luo, Yixiong Cao, Feng Wen, Junjun Li, Xi Chen, Fujue Wang
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11603458

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