The arms race of ray-finned fish against the derepression of LTR retroelements
Elisa Carotti, Edith Tittarelli, Federica Carducci, Marco Barucca, Adriana Canapa, Maria Assunta Biscotti · 2024
Read The arms race of ray-finned fish against the derepression of LTR retroelements by Elisa Carotti, Edith Tittarelli, Federica Carducci, Marco Barucca, Adriana Canapa, Maria Assunta Biscotti (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11603059.txt.
Description
Elisa Carotti and co-authors study how ray-finned fish silence the jumping genes in their own DNA, in a 2024 paper. Jumping genes can copy themselves around the genome, and cells keep them muzzled with special proteins. In land animals with backbones, one muzzle system is well mapped. Fish lack two of its key parts, yet their jumping genes stay quiet, so some stand-in must do the job.
The team guessed a related protein fills the gap. They tested whether it grips the fish versions of the muzzle's other parts in two species: a marbled eel, an early branch of the bony fish line, and the zebrafish. They also tracked jumping gene activity as zebrafish embryos grow. The results support an alternate muzzle built from parts at hand. The authors frame it as an arms race in which fish forged their own weapons.
Catalog record
| CREATOR | Elisa Carotti, Edith Tittarelli, Federica Carducci, Marco Barucca, Adriana Canapa, Maria Assunta Biscotti |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |