Epstein–Barr Virus and gastric carcinoma pathogenesis with emphasis on underlying epigenetic mechanisms
Fatemeh Estaji, Saeed Zibaee, Maryam Torabi, Sharareh Moghim · 2024
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Description
Fatemeh Estaji and co-authors present a 2024 review of Epstein-Barr virus in stomach cancer. Stomach cancer stays a top cause of cancer death worldwide. Its causes join lifestyle, family history, gene faults, and infections. Epstein-Barr virus infects over ninety-five percent of people, usually silently for life. It was the first virus found in a human tumor. Its role in stomach cancer is now a settled research topic, though key mechanisms stay disputed.
The review centers on epigenetic mechanisms: chemical marks that switch genes without changing DNA. Immune shifts and gene mutations get coverage as well. Contradictions on whether the virus worsens outlook are weighed openly. Oncologists get a map of how a near-universal virus can drive one cancer in a small minority. That minority question is the puzzle: the marks the virus leaves may explain why only some carriers develop tumors.
Catalog record
| CREATOR | Fatemeh Estaji, Saeed Zibaee, Maryam Torabi, Sharareh Moghim |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |