Susceptibility to and severity of SARS-CoV-2 infection according to prescription drug use–an observational study of 46,506 Danish healthcare workers

Aleksander Eiken, Sofie Bliddal, Marie Villumsen, Kasper K. Iversen, Henning Bundgaard, Rasmus B. Hasselbach, Jonas H. Kristensen, Pernille B. Nielsen, Mia M. Pries-Heje, Andreas D. Knudsen, Kamille Fogh, Jakob B. Norsk, Ove Andersen, Thea K. Fischer, Ram B. Dessau, Sisse R. Ostrowski, Christian Tor · 2024

Read Susceptibility to and severity of SARS-CoV-2 infection according to prescription drug use–an observational study of 46,506 Danish healthcare workers by Aleksander Eiken, Sofie Bliddal, Marie Villumsen, Kasper K. Iversen, Henning Bundgaard, Rasmus B. Hasselbach, Jonas H. Kristensen, Pernille B. Nielsen, Mia M. Pries-Heje, Andreas D. Knudsen, Kamille Fogh, Jakob B. Norsk, Ove Andersen, Thea K. Fischer, Ram B. Dessau, Sisse R. Ostrowski, Christian Tor (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11602038.txt.

Description

Aleksander Eiken and co-authors scan prescription drug use for links with COVID-19 risk in Danish health workers, in this 2024 study. Which drug classes make infection more or less likely, or illness more severe, was not well mapped. The team drew on national health registers and worker surveys from 2020.

They matched 5,710 infected workers with 57,021 uninfected controls of like age, sex, and chronic disease. Use of calcium channel blockers and vessel-protecting drugs in the prior six months went with lower odds of infection. Antibacterial use in the prior month went with higher odds. Among those infected, users of nearly any drug studied had higher odds of severe illness, most of all users of water pills and airway drugs. The authors read the pattern with care: drug use may mark underlying illness or behavior rather than cause the outcomes, and they call for studies that tease the two apart.

Catalog record

CREATORAleksander Eiken, Sofie Bliddal, Marie Villumsen, Kasper K. Iversen, Henning Bundgaard, Rasmus B. Hasselbach, Jonas H. Kristensen, Pernille B. Nielsen, Mia M. Pries-Heje, Andreas D. Knudsen, Kamille Fogh, Jakob B. Norsk, Ove Andersen, Thea K. Fischer, Ram B. Dessau, Sisse R. Ostrowski, Christian Tor
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE46 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11602038

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