Role of neutrophils in the pathogenesis of Post Kala-azar Dermal Leishmaniasis (PKDL)

Madhurima Roy, Ritika Sengupta, Bidhan Chandra Chakraborty, Uttara Chatterjee, Esther von Stebut, Paul M. Kaye, Mitali Chatterjee · 2024

Read Role of neutrophils in the pathogenesis of Post Kala-azar Dermal Leishmaniasis (PKDL) by Madhurima Roy, Ritika Sengupta, Bidhan Chandra Chakraborty, Uttara Chatterjee, Esther von Stebut, Paul M. Kaye, Mitali Chatterjee (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11602034.txt.

Description

Madhurima Roy and co-authors study white blood cells in a skin disease in 2024. The disease follows a severe parasite infection of the inner organs. It leaves skin lesions that can keep the parasite cycle alive and threaten control programs. Neutrophils are first responders in the organ disease, but their role in the skin form was unclear.

The team counted neutrophils in skin samples from patients. They stained the samples to spot active and spent forms of the cells. They also tracked enzymes the cells release and the skin protein they may harm. The work probes whether these early defenders help or hurt in the skin stage.

Catalog record

CREATORMadhurima Roy, Ritika Sengupta, Bidhan Chandra Chakraborty, Uttara Chatterjee, Esther von Stebut, Paul M. Kaye, Mitali Chatterjee
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE46 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11602034

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