Combination Low-Dose Pilocarpine/Diclofenac Sodium and Pilocarpine Alone for Presbyopia: Results of a Randomized Phase 2b Clinical Trial
Marjan Farid, Sheri L Rowen, Majid Moshirfar, Derek Cunningham, Ian B Gaddie, Gerard Smits, Teresa Ignacio, Preeya K Gupta · 2024
Read Combination Low-Dose Pilocarpine/Diclofenac Sodium and Pilocarpine Alone for Presbyopia: Results of a Randomized Phase 2b Clinical Trial by Marjan Farid, Sheri L Rowen, Majid Moshirfar, Derek Cunningham, Ian B Gaddie, Gerard Smits, Teresa Ignacio, Preeya K Gupta (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11600938.txt.
Description
Marjan Farid and others reported a 2024 clinical trial of eye drops meant to treat presbyopia, the age-related loss of near focus. Adults in their mid forties to mid sixties were assigned at random to drops containing pilocarpine alone. Others got drops combining pilocarpine with a small amount of diclofenac, or a control drop with diclofenac only.
Doses rose partway through the two-week trial. The main test measured whether eyes gained at least three lines on a near-vision chart an hour after treatment. Results from trials like this one help regulators judge whether a daily drop could free some middle-aged readers from relying on glasses for close work.
Catalog record
| CREATOR | Marjan Farid, Sheri L Rowen, Majid Moshirfar, Derek Cunningham, Ian B Gaddie, Gerard Smits, Teresa Ignacio, Preeya K Gupta |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |