Transcutaneous auricular vagus nerve stimulation in anesthetized mice induces antidepressant effects by activating dopaminergic neurons in the ventral tegmental area
Tae-Yong Choi, Jeongseop Kim, Ja Wook Koo · 2024
Read Transcutaneous auricular vagus nerve stimulation in anesthetized mice induces antidepressant effects by activating dopaminergic neurons in the ventral tegmental area by Tae-Yong Choi, Jeongseop Kim, Ja Wook Koo (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11600629.txt.
Description
Tae-Yong Choi, Jeongseop Kim, and Ja Wook Koo test a mild electric pulse at the ear as a way to ease low mood in mice in 2024. The pulse targets a nerve that links ear and brain. Low mood involves a drop in a brain chemical tied to drive and reward. The team asked if the pulse works through that chemical system.
Mice that got the pulse while asleep showed fewer signs of low mood. The pulse raised activity in a brain area rich in that chemical. When those cells were blocked, the gain from the pulse was lost. The results suggest the ear pulse lifts mood by waking that brain area. More work is needed before use in people.
Catalog record
| CREATOR | Tae-Yong Choi, Jeongseop Kim, Ja Wook Koo |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 13 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |