Different storage and freezing protocols for extracellular vesicles: a systematic review
Shahin Ahmadian, Negin Jafari, Amin Tamadon, Alireza Ghaffarzadeh, Reza Rahbarghazi, Mahdi Mahdipour · 2024
Read Different storage and freezing protocols for extracellular vesicles: a systematic review by Shahin Ahmadian, Negin Jafari, Amin Tamadon, Alireza Ghaffarzadeh, Reza Rahbarghazi, Mahdi Mahdipour (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11600612.txt.
Description
Shahin Ahmadian and five co-authors review how to store tiny cell-made vesicles without ruining them. Extracellular vesicles are promising tools for regenerative medicine, but their nanoscale size makes them fragile. Their 2024 systematic review gathers studies on storage temperature, freezing methods, repeated freeze-thaw cycles, and stabilizing additives. Outcomes tracked include how many vesicles survive, their size, and whether they still work.
A therapy that degrades on the shelf is no therapy at all. Labs currently improvise storage, so results vary for reasons nobody reports. The review aims to turn scattered findings into shared practice. Comparing protocols side by side shows which choices protect the vesicles best. The authors write for both researchers and future manufacturers. Storage, unglamorous as it sounds, decides whether the field scales.
Catalog record
| CREATOR | Shahin Ahmadian, Negin Jafari, Amin Tamadon, Alireza Ghaffarzadeh, Reza Rahbarghazi, Mahdi Mahdipour |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 100 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |