One year of ETI reduces lung bacterial colonisation in adults with cystic fibrosis

Lucile Mianowski, Anne Doléans-Jordheim, Laurent Barraud, Muriel Rabilloud, Mael Richard, Raphaele Nove Josserand, Isabelle Durieu, Quitterie Reynaud · 2024

Read One year of ETI reduces lung bacterial colonisation in adults with cystic fibrosis by Lucile Mianowski, Anne Doléans-Jordheim, Laurent Barraud, Muriel Rabilloud, Mael Richard, Raphaele Nove Josserand, Isabelle Durieu, Quitterie Reynaud (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11599715.txt.

Description

Lucile Mianowski and colleagues tracked lung bacteria during cystic fibrosis therapy in two thousand twenty-four. A triple drug combination transformed disease outcomes recently. Lung germ colonization may change under treatment too. French adults supplied sputum cultures over years. Records covered three years before treatment started. Follow-up ran one year after starting.

Colonization by any typical pathogen fell significantly. Several major germs declined individually as well. Bacterial density in sputum dropped sharply. Chronic colonization with the worst germ also decreased. Lung function and hospital stays were tracked alongside. The therapy appears to lighten lung infection burden. Longer watching will confirm durability.

Catalog record

CREATORLucile Mianowski, Anne Doléans-Jordheim, Laurent Barraud, Muriel Rabilloud, Mael Richard, Raphaele Nove Josserand, Isabelle Durieu, Quitterie Reynaud
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11599715

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