Immune environment of high-TIL breast cancer: triple negative and hormone receptor positive HER2 negative
Su-Jin Shin, Inho Park, Heounjeong Go, Jiwon Ko, Yangkyu Lee, Jee Hung Kim, Sung Gwe Ahn, Joon Jeong, Soong June Bae, Yoon Jin Cha · 2024
Read Immune environment of high-TIL breast cancer: triple negative and hormone receptor positive HER2 negative by Su-Jin Shin, Inho Park, Heounjeong Go, Jiwon Ko, Yangkyu Lee, Jee Hung Kim, Sung Gwe Ahn, Joon Jeong, Soong June Bae, Yoon Jin Cha (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11599379.txt.
Description
Su-Jin Shin and co-authors compare immune cells inside two kinds of breast cancer with high immune cell counts. Their 2024 paper uses tissue from 32 removed tumors, split between triple negative cases and hormone-linked cases. Stained slides let the team count cell types and map where they sat.
Triple negative tumors held more killer T cells in both the tumor core and the rim around it. They also held more of a helper cell type linked to immune control. A surface marker called PD-L1 changed the cell mix in both cancer kinds. In marker-positive triple negative cases, control-type cells packed more densely near tumor cells. The maps may help guide immune care choices.
Catalog record
| CREATOR | Su-Jin Shin, Inho Park, Heounjeong Go, Jiwon Ko, Yangkyu Lee, Jee Hung Kim, Sung Gwe Ahn, Joon Jeong, Soong June Bae, Yoon Jin Cha |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |