Beneficial Effects of Micronutrient Supplementation in Restoring the Altered Microbiota and Gut–Retina Axis in Patients with Neovascular Age-Related Macular Degeneration—A Randomized Clinical Trial
Simone Baldi, Giuditta Pagliai, Leandro Di Gloria, Marco Pallecchi, Francesco Barca, Benedetta Pieri, Gianluca Bartolucci, Matteo Ramazzotti, Amedeo Amedei, Gianna Palendri, Francesco Sofi · 2024
Read Beneficial Effects of Micronutrient Supplementation in Restoring the Altered Microbiota and Gut–Retina Axis in Patients with Neovascular Age-Related Macular Degeneration—A Randomized Clinical Trial by Simone Baldi, Giuditta Pagliai, Leandro Di Gloria, Marco Pallecchi, Francesco Barca, Benedetta Pieri, Gianluca Bartolucci, Matteo Ramazzotti, Amedeo Amedei, Gianna Palendri, Francesco Sofi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11597754.txt.
Description
Simone Baldi and co-authors test whether eye-health supplements also repair the gut in patients with wet age-related macular degeneration, in a trial published in 2024. The disease blinds older adults, and evidence links it to the gut-retina axis, the biochemical conversation between intestinal microbes and the eye. Thirty patients receiving standard anti-VEGF injections were randomized to add a daily supplement of lutein, zeaxanthin, and saffron, or not.
Before treatment, patients' gut microbes were less diverse than healthy controls'. Over six months the team tracked vision measures, blood chemistry, and stool microbes and fatty acids. The report's title announces beneficial effects on the altered microbiota. The design isolates the supplement's contribution because both arms received the same injections, a tidy test of the axis idea.
Catalog record
| CREATOR | Simone Baldi, Giuditta Pagliai, Leandro Di Gloria, Marco Pallecchi, Francesco Barca, Benedetta Pieri, Gianluca Bartolucci, Matteo Ramazzotti, Amedeo Amedei, Gianna Palendri, Francesco Sofi |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |