Optimizing Red Light-Based Photodynamic Therapy for Effective Bactericidal Action Against Fusobacterium nucleatum Subspecies
Jianglan Li, Takayuki Nambu, Chao Wang, Hiroki Takigawa, Hugo Maruyama, Chiho Mashimo, Toshinori Okinaga · 2024
Read Optimizing Red Light-Based Photodynamic Therapy for Effective Bactericidal Action Against Fusobacterium nucleatum Subspecies by Jianglan Li, Takayuki Nambu, Chao Wang, Hiroki Takigawa, Hugo Maruyama, Chiho Mashimo, Toshinori Okinaga (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11597717.txt.
Description
Dentists in Japan tune a light-based cure for a mouth germ tied to gum disease. The germ helps mouth films mature and has links to bowel cancer and liver disease far from the mouth. The cure feeds the germ a safe acid that makes it stock a light-sensitive dye. Red light then wakes the dye, which kills the germ from inside. No past work had set the best dose of acid or light for this germ.
The team grew four strains of the germ with a range of acid doses in air-free jars. Dye stock was read by its glow, and live counts told how many germs died after light. Most strains died well at a low acid dose, and dye stock tracked death rates closely. The team names the best mix of acid dose and light strength for clinic tests.
Catalog record
| CREATOR | Jianglan Li, Takayuki Nambu, Chao Wang, Hiroki Takigawa, Hugo Maruyama, Chiho Mashimo, Toshinori Okinaga |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |