Matrix Solid-Phase Dispersion Procedure for Determination of Antibiotics and Metabolites in Mussels: Application in Exposure Bioassays

Carmen Mejías, Tainá G Fonseca, Noelia García-Criado, Julia Martín, Juan Luis Santos, Irene Aparicio, Esteban Alonso, Irene Panderi · 2024

Read Matrix Solid-Phase Dispersion Procedure for Determination of Antibiotics and Metabolites in Mussels: Application in Exposure Bioassays by Carmen Mejías, Tainá G Fonseca, Noelia García-Criado, Julia Martín, Juan Luis Santos, Irene Aparicio, Esteban Alonso, Irene Panderi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11597543.txt.

Description

The authors develop a method to measure antibiotics inside mussels in a 2024 paper. Traces of drugs in seafood can reach consumers. Mussels also serve as signs of marine pollution. One-step extraction plus cleanup anchors the method.

Three sulphonamide drugs and a partner compound were the aim. Six breakdown products joined the analyte list. Dispersion extraction with a common solvent did the prep work. Liquid chromatography with tandem mass detection finished the job. Linearity, accuracy, and sensitivity all checked well. Detection limits sat below five nanograms per gram. Mussels put in spiked sea water tested the workflow. Both spiked drugs showed in the tissue. One built up more, matching its fattier chemistry. No metabolites were found in these samples. The species earned its status as a living sign of pollution. Food safety labs gain a protocol for many drugs at once.

Catalog record

CREATORCarmen Mejías, Tainá G Fonseca, Noelia García-Criado, Julia Martín, Juan Luis Santos, Irene Aparicio, Esteban Alonso, Irene Panderi
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11597543

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