The Acid-Buffered Engineered Gel Promotes In Vitro Cutaneous Healing and Fights Resistant Bacteria in Wounds
Fatima Abid, Emmeline Virgo, Tahlia Louise Kennewell, Riya Khetan, Hanif Haidari, Zlatko Kopecki, Yunmei Song, Sanjay Garg, Natascia Mennini · 2024
Read The Acid-Buffered Engineered Gel Promotes In Vitro Cutaneous Healing and Fights Resistant Bacteria in Wounds by Fatima Abid, Emmeline Virgo, Tahlia Louise Kennewell, Riya Khetan, Hanif Haidari, Zlatko Kopecki, Yunmei Song, Sanjay Garg, Natascia Mennini (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11597482.txt.
Description
Chronic wounds stall when bacteria settle in, and two germs lead the offenders. Fatima Abid and co-authors fight them with an acid-buffered alginate gel in this 2024 study, tuned to a pH of 4.5. Three versions varied the acid load. The gels held their acidity against alkaline fluids that mimic wound juice at different states.
All three killed common wound bacteria in lab tests, including drug-resistant strains. The stronger two cut bacteria inside stubborn biofilms of both lead germs. The mildest gel kept skin cells thriving above 80 percent and helped close a scratch wound model fastest. The authors propose the mild gel for healing support and the stronger ones where infection dominates. Human wound trials come next.
Catalog record
| CREATOR | Fatima Abid, Emmeline Virgo, Tahlia Louise Kennewell, Riya Khetan, Hanif Haidari, Zlatko Kopecki, Yunmei Song, Sanjay Garg, Natascia Mennini |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |