Odd-Numbered Agaro-Oligosaccharides Produced by α-Neoagaro-Oligosaccharide Hydrolase Exert Antioxidant Activity in Human Dermal Fibroblasts
Eunyoung Jo, Navindu Dinara Gajanayaka, Minthari Sakethanika Bandara, Svini Dileepa Marasinghe, Gun-Hoo Park, Su-Jin Lee, Chulhong Oh, Youngdeuk Lee, Olafur Fridjonsson · 2024
Read Odd-Numbered Agaro-Oligosaccharides Produced by α-Neoagaro-Oligosaccharide Hydrolase Exert Antioxidant Activity in Human Dermal Fibroblasts by Eunyoung Jo, Navindu Dinara Gajanayaka, Minthari Sakethanika Bandara, Svini Dileepa Marasinghe, Gun-Hoo Park, Su-Jin Lee, Chulhong Oh, Youngdeuk Lee, Olafur Fridjonsson (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11595537.txt.
Description
Eunyoung Jo and eight co-authors published a 2024 study on sugars made from agar, the gel from red seaweed. An enzyme that cuts agar chains makes an unusual set of odd numbered sugar pieces. The team tested whether those pieces can protect skin cells from oxidative damage.
The enzyme came from a marine bacterium that feeds on agar. The team made it in lab bacteria, purified it, and mapped how it works best. It liked a mildly acidic setting and mild warmth, and a manganese salt boosted its action. It cut three sizes of starting sugar into the odd numbered products. Those products then showed antioxidant activity in human skin cells grown in the lab. Such sugars could find use in skin care or food products.
Catalog record
| CREATOR | Eunyoung Jo, Navindu Dinara Gajanayaka, Minthari Sakethanika Bandara, Svini Dileepa Marasinghe, Gun-Hoo Park, Su-Jin Lee, Chulhong Oh, Youngdeuk Lee, Olafur Fridjonsson |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |