T-Type Voltage-Gated Calcium Channels: Potential Regulators of Smooth Muscle Contractility
Shota Tomida, Tamaki Ishima, Ryozo Nagai, Kenichi Aizawa, Juan A Rosado · 2024
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Description
Shota Tomida and co-authors review a quiet calcium channel that may steer blood vessel tightening. Their 2024 paper deals with T-type voltage-gated calcium channels in smooth muscle. The better known L-type channels draw most study, yet fresh multi-omic reads of weak aortas point elsewhere. In models of inherited aortic swelling and tearing, loss of squeeze tracked a drop in T-type channels, not L-type ones.
The review maps the channel's build, firing traits, body spread, and jobs. It then asks how losing the channel could blunt muscle squeeze and feed vessel failure. Multi-omic hunts earn a part too. The authors frame T-type channels as a fresh lead for vessel disease work.
Catalog record
| CREATOR | Shota Tomida, Tamaki Ishima, Ryozo Nagai, Kenichi Aizawa, Juan A Rosado |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |