Dissecting the Impact of Genetic Background on Oncogenic Response to Radiation Exposure in the Ptch1+/− Mouse Model
Barbara Tanno, Emiliano Fratini, Simona Leonardi, Flavia Novelli, Valentina Pisano, Mariateresa Mancuso, Simonetta Pazzaglia · 2024
Read Dissecting the Impact of Genetic Background on Oncogenic Response to Radiation Exposure in the Ptch1+/− Mouse Model by Barbara Tanno, Emiliano Fratini, Simona Leonardi, Flavia Novelli, Valentina Pisano, Mariateresa Mancuso, Simonetta Pazzaglia (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11593216.txt.
Description
A child brain cancer can be sparked when a growth path stays on in the young back brain. Barbara Tanno and co-authors use mice in a 2024 study to ask why the same gene fault leads to cancer in one mouse breed and not in a twin breed. Both breeds carry a half fault in the path's brake gene, and rays at birth lift cancer rates a lot.
Cells from the touchy breed felt rays more than cells from the firm breed. Gene reads split the two breeds' tumours by a five gene sign. That sign rose with rays in the touchy breed's grown tumours, but not in the firm breed's. The sign may flag how a tumour will reply to ray care.
Catalog record
| CREATOR | Barbara Tanno, Emiliano Fratini, Simona Leonardi, Flavia Novelli, Valentina Pisano, Mariateresa Mancuso, Simonetta Pazzaglia |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |