Update on the Biological and Clinical Relevance of Mast Cells in Chronic Rhinosinusitis with Nasal Polyps
Luca Giovanni Locatello, Silvia Tonon, Vincenzo Mele, Simone Santini, Cesare Miani, Carlo Ennio Michele Pucillo · 2024
Read Update on the Biological and Clinical Relevance of Mast Cells in Chronic Rhinosinusitis with Nasal Polyps by Luca Giovanni Locatello, Silvia Tonon, Vincenzo Mele, Simone Santini, Cesare Miani, Carlo Ennio Michele Pucillo (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11592168.txt.
Description
Luca Giovanni Locatello and co-authors review the role of mast cells in a stubborn sinus disease in this 2024 update. The disease brings nasal polyps and lasting inflammation of the sinuses. Its most common form is driven mainly by eosinophils, a type of white blood cell.
Care has long rested on steroid sprays, steroid pills, and sinus surgery. New biologic drugs now target key signals such as IL-4, IL-5, and IL-13. Mast cells sit inside this inflammation story and may shape who responds to treatment. The review pulls together biology and clinic evidence. It helps doctors judge where mast cells fit in modern care. Specialists who treat severe sinus disease will find it most useful.
Catalog record
| CREATOR | Luca Giovanni Locatello, Silvia Tonon, Vincenzo Mele, Simone Santini, Cesare Miani, Carlo Ennio Michele Pucillo |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |