Advanced Parameters of Myocardial Strain and Cardiac Biomarkers Indicate Subclinical Systolic Myocardial Dysfunction in Patients with Systemic Lupus Erythematous
Nikolaos P E Kadoglou, Alexandriani Dimopoulou, Ioannis Korakianitis, Konstantinos Parperis, Anand Prakash Singh · 2024
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Description
Lupus quietly damages the heart long before symptoms, and Nikolaos Kadoglou and co-authors hunt the early signs in a 2024 study of about one hundred patients with no known heart trouble. Ultrasound strain imaging measured how the heart muscle deforms, and blood carried three stress markers. Against healthy controls, the patients' deformation was weaker and wasted work higher.
Both groups' strain gap was clear, and two blood markers ran two to three times higher in patients, rising further when the disease flared. The authors argue pairing strain imaging with blood markers can flag hidden heart weakness in time to act.
Catalog record
| CREATOR | Nikolaos P E Kadoglou, Alexandriani Dimopoulou, Ioannis Korakianitis, Konstantinos Parperis, Anand Prakash Singh |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |