Activins and Inhibins in Cardiovascular Pathophysiology
Wenyi Tang, Zhilin Gu, Jiuqi Guo, Mingzhi Lin, Hongqian Tao, Dalin Jia, Pengyu Jia · 2024
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Description
Wenyi Tang and co-authors review two hormone families in a 2024 paper. Activins and inhibins were first known for opposed effects on a pituitary hormone. Wider roles across many tissues have since emerged. They signal mainly through a classic pathway, with other routes in play. Their action is complex and depends on context.
Recent work ties both families to heart and vessel disease. Signals from other organs also track with heart disease growth. The review sums biological roles, mechanisms, and heart findings in one place. Heart researchers get a map of two factors long filed under reproduction. Cross-system signals are easy to miss in organ-siloed research. If these factors drive part of heart disease, they offer fresh drug targets. The authors frame the field as young, with mechanism gaps still open.
Catalog record
| CREATOR | Wenyi Tang, Zhilin Gu, Jiuqi Guo, Mingzhi Lin, Hongqian Tao, Dalin Jia, Pengyu Jia |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |