Gut Microbe-Generated Metabolite Trimethylamine-N-Oxide and Ischemic Stroke
Zhen Li, Xinyi He, Qi Fang, Xulong Yin, Hongmin Wang, Konstantinos Tziomalos · 2024
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Description
Zhen Li and co-authors review what is known about TMAO, a substance made when gut microbes process certain foods, and its links to stroke caused by blocked blood flow to the brain. The body makes TMAO from food with help from gut bacteria and the liver, and the kidneys clear it out. Higher blood levels of it have been tied to a higher risk of heart and blood vessel disease.
The review walks through how TMAO may raise stroke risk. It can help fatty deposits grow in artery walls, make blood more prone to clot, and harm the lining of blood vessels. The authors also sum up studies on ways to lower TMAO through diet and gut care. They note that some links, such as how it affects recovery after a stroke, are still not clear and need more work.
Catalog record
| CREATOR | Zhen Li, Xinyi He, Qi Fang, Xulong Yin, Hongmin Wang, Konstantinos Tziomalos |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |