Methyl Paraben Affects Porcine Oocyte Maturation Through Mitochondrial Dysfunction
Huimei Huang, Chuman Huang, Yinghua Li, Xingwei Liang, Namhyung Kim, Yongnan Xu · 2024
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Description
Huimei Huang and co-authors test what a common cosmetic preservative does to eggs maturing in a dish. Methyl paraben keeps microbes out of foods, drugs, and baby products, and it mimics estrogen in the body. Earlier work showed harm to sperm-side cells. Their 2024 study uses pig oocytes, a standard stand-in for human eggs.
Exposed eggs expanded less, switched on expansion genes more weakly, and released their first polar body less often — a plain sign of stalled maturation. Energy output from the mitochondria fell. The team traces the damage to failing mitochondria inside the egg. Reproductive toxicologists get a mechanism, not just a warning, for a chemical found in daily products.
Catalog record
| CREATOR | Huimei Huang, Chuman Huang, Yinghua Li, Xingwei Liang, Namhyung Kim, Yongnan Xu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |