Real-world patient characteristics and survival outcomes in patients with advanced or recurrent endometrial cancer in England: a retrospective, population-based study

Susana Banerjee, Alvaro Ingles Russo Garces, Jamie Garside, Tameera Rahman, Clare Pearson, Kiera Heffernan · 2024

Read Real-world patient characteristics and survival outcomes in patients with advanced or recurrent endometrial cancer in England: a retrospective, population-based study by Susana Banerjee, Alvaro Ingles Russo Garces, Jamie Garside, Tameera Rahman, Clare Pearson, Kiera Heffernan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11590861.txt.

Description

Susana Banerjee and co-authors describe real-world outcomes for advanced womb cancer in England in a 2024 study. The cancer, of the lining of the womb, often returns after first treatment and then has few good options. New immune drugs are being tested for first-line use, and trial results need a real-world baseline for comparison.

Using national registry data, the team built a cohort of patients who would likely have qualified for a major immune drug trial. Median survival after first treatment was about twenty-seven months. In the subgroup treated only with a standard two-drug chemotherapy, survival was much shorter, at about seventeen months. Treatment was stopped after a few months in both groups. The authors say the poor outcomes show the need for more durable therapies.

Catalog record

CREATORSusana Banerjee, Alvaro Ingles Russo Garces, Jamie Garside, Tameera Rahman, Clare Pearson, Kiera Heffernan
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11590861

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