The impact of qualitative [18F]FDG PET/CT in predicting clinical outcomes of post-surgical differentiated thyroid cancer patients with elevated thyroglobulin and negative radioiodine whole-body scan

Le Ngoc Ha, Nguyen Thi Phuong, Mai Hong Son · 2024

Read The impact of qualitative [18F]FDG PET/CT in predicting clinical outcomes of post-surgical differentiated thyroid cancer patients with elevated thyroglobulin and negative radioiodine whole-body scan by Le Ngoc Ha, Nguyen Thi Phuong, Mai Hong Son (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11590570.txt.

Description

Le Ngoc Ha, Nguyen Thi Phuong, and Mai Hong Son use PET imaging to forecast thyroid cancer outcomes in a 2024 study. Some post-surgical patients show high tumor marker levels but negative iodine scans. That pattern, called TENIS syndrome, hides where disease persists. FDG PET scans can localize such non-avid lesions.

Patients treated from 2019 to 2023 at one hospital were collected. Scans were classed as negative, minimal, or extensive by lesion volume. Survival without progression and overall survival were the endpoints. One hundred sixty-four patients entered the analysis. Papillary cancer dominated the histology as expected. Survival curves split clearly by scan category. Regression models sought independent predictors of both endpoints. Qualitative scan reading thus carries prognostic weight beyond detection. The authors argue scan volume should inform follow-up intensity. Prospective checks would strengthen the claim.

Catalog record

CREATORLe Ngoc Ha, Nguyen Thi Phuong, Mai Hong Son
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11590570

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