Effect of low-dose dexmedetomidine to prolong spinal anesthesia in elderly patients: a prospective randomized controlled study
Lisa Sangkum, Sivaporn Termpornlert, Choosak Tunprasit, Chatchayapa Rathanasutthajohn, Rojnarin Komonhirun, Sasima Dusitkasem · 2024
Read Effect of low-dose dexmedetomidine to prolong spinal anesthesia in elderly patients: a prospective randomized controlled study by Lisa Sangkum, Sivaporn Termpornlert, Choosak Tunprasit, Chatchayapa Rathanasutthajohn, Rojnarin Komonhirun, Sasima Dusitkasem (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11590567.txt.
Description
Lisa Sangkum and co-authors ran this 2024 randomized trial on stretching spinal anesthesia in older men having prostate surgery. Spinal blocks for this operation wear off quickly, leaving a pain-management gap. Thirty-eight patients aged sixty to eighty received either a low intravenous dose of dexmedetomidine, a sedative known to deepen blocks, or saline, right after the spinal injection.
The block faded measurably slower with the drug: the two-level regression time stretched from about eighty-one to one hundred four minutes. Peak block height also rose. Low blood pressure, slow heart rate, and pain scores over the first day did not differ between groups. The authors conclude a small sedative dose safely buys extra anesthesia time in elderly patients.
Catalog record
| CREATOR | Lisa Sangkum, Sivaporn Termpornlert, Choosak Tunprasit, Chatchayapa Rathanasutthajohn, Rojnarin Komonhirun, Sasima Dusitkasem |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |