Longitudinal history of mammographic breast density and breast cancer risk by familial risk, menopausal status, and initial mammographic density level in a high risk cohort: a nested case–control study
Parisa Tehranifar, Erica J Lee Argov, Shweta Athilat, Yuyan Liao, Ying Wei, Alexandra J White, Katie M O’Brien, Dale P Sandler, Mary Beth Terry · 2024
Read Longitudinal history of mammographic breast density and breast cancer risk by familial risk, menopausal status, and initial mammographic density level in a high risk cohort: a nested case–control study by Parisa Tehranifar, Erica J Lee Argov, Shweta Athilat, Yuyan Liao, Ying Wei, Alexandra J White, Katie M O’Brien, Dale P Sandler, Mary Beth Terry (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11590558.txt.
Description
Parisa Tehranifar and eight co-authors asked whether changes in breast density over time predict breast cancer, in a 2024 study. Dense breast tissue on mammograms is a known risk factor. Less was known about the path density takes. The team used a cohort of women with family history of the disease. Over twelve thousand mammograms were analyzed.
Cases had higher starting density and slower declines than controls. Women whose density stayed stable faced higher risk than women with steep yearly drops. Rising dense area raised risk further, most in women starting with the most dense tissue. Patterns were similar across menopause and family risk groups. Links looked stronger in pre-menopausal and lower-risk women. The authors suggest tracking density paths in risk checks. Women without declines may merit closer monitoring.
Catalog record
| CREATOR | Parisa Tehranifar, Erica J Lee Argov, Shweta Athilat, Yuyan Liao, Ying Wei, Alexandra J White, Katie M O’Brien, Dale P Sandler, Mary Beth Terry |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |