Epigenetic mechanisms mediate cytochrome P450 1A1 expression and lung endothelial injury caused by MRSA in vitro and in vivo
Alison W. Ha, Lucille N. Meliton, Weiguo Chen, Lichun Wang, Mark Maienschein‐Cline, Jeffrey R. Jacobson, Eleftheria Letsiou, Steven M. Dudek · 2024
Read Epigenetic mechanisms mediate cytochrome P450 1A1 expression and lung endothelial injury caused by MRSA in vitro and in vivo by Alison W. Ha, Lucille N. Meliton, Weiguo Chen, Lichun Wang, Mark Maienschein‐Cline, Jeffrey R. Jacobson, Eleftheria Letsiou, Steven M. Dudek (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11590412.txt.
Description
Methicillin‐resistant Staphylococcus aureus (MRSA) is a common cause of severe pneumonia and acute respiratory distress syndrome (ARDS). To advance our mechanistic understanding of this important pathogen, we characterized the effects of MRSA‐induced epigenetic modification of histone 3 lysine 9 acetylation (H3K9ac), an activator of gene transcription, on lung endothelial cells (EC), a critical site of ARDS pathophysiology.
Catalog record
| CREATOR | Alison W. Ha, Lucille N. Meliton, Weiguo Chen, Lichun Wang, Mark Maienschein‐Cline, Jeffrey R. Jacobson, Eleftheria Letsiou, Steven M. Dudek |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |