Integrated bioinformatics analysis reveals that CCBP2 and GPR87 are new GPCR-associated biomarkers for preeclampsia
Jie Li, Meng-Meng Chen, Bingqiang Zhang, Yi Zhao · 2024
Read Integrated bioinformatics analysis reveals that CCBP2 and GPR87 are new GPCR-associated biomarkers for preeclampsia by Jie Li, Meng-Meng Chen, Bingqiang Zhang, Yi Zhao (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11590348.txt.
Description
Jie Li, Meng-Meng Chen, Bingqiang Zhang, and Yi Zhao search for new markers of preeclampsia, a dangerous pregnancy syndrome. Their 2024 study focuses on G protein-coupled receptors, a large family of cell surface switches. The disease lacks good early tests and firm treatments, so fresh markers carry real weight.
Using a network method that groups genes by shared patterns, the team flagged two receptors as central: CCBP2 and GPR87. Lab tests then showed that both slow the growth, movement, and invasion of trophoblast cells, the placental cells whose failure sits at the heart of the disease. The authors offer the pair as candidates for diagnosis and for future drug work.
Catalog record
| CREATOR | Jie Li, Meng-Meng Chen, Bingqiang Zhang, Yi Zhao |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |