Application of RhBMP-2 in Percutaneous Endoscopic Posterior Lumbar Interbody Fusion
Yunsheng Chen, Canhua Xu, Yaohong Wu, Jiangyou Shi, Rongchun Chen · 2024
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Description
Yunsheng Chen and four co-authors present a 2024 trial on a growth protein used in a keyhole spine fusion operation. The operation joins two lumbar vertebrae through small incisions, and the graft material affects whether the bones fuse. The team randomly split 102 patients: half received the protein, RhBMP-2, and half their own harvested bone. Both groups also had screw fixation, and outcomes were tracked for a year.
Surgery time, blood loss, and complications matched between groups. At twelve months the protein group fused far more often, about 86 percent against 55 percent, and their graft cages slipped less. Their function and quality-of-life scores also ended higher, with better disc height and less vertebral slippage. The authors conclude the protein restores function and promotes fusion better than the patient's own bone in this operation.
Catalog record
| CREATOR | Yunsheng Chen, Canhua Xu, Yaohong Wu, Jiangyou Shi, Rongchun Chen |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |