The combination of CSF neurofilament light chain and glial fibrillary acidic protein improves the prediction of long-term confirmed disability worsening in multiple sclerosis
Simon Thebault, Seyed-Mohammad Fereshtehnejad, Hailey P Bergman, Gautier Breville, Mohammad Abdoli, Ronald A Booth, Giulia Fadda, Mark S Freedman, Gauruv Bose · 2024
Read The combination of CSF neurofilament light chain and glial fibrillary acidic protein improves the prediction of long-term confirmed disability worsening in multiple sclerosis by Simon Thebault, Seyed-Mohammad Fereshtehnejad, Hailey P Bergman, Gautier Breville, Mohammad Abdoli, Ronald A Booth, Giulia Fadda, Mark S Freedman, Gauruv Bose (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11589836.txt.
Description
Simon Thebault and eight co-workers wrote a 2024 study on two spinal fluid markers that foresee disability growth in multiple sclerosis. One marker tracks nerve fiber harm, the other tracks support cell activity. The team had paired blood and spinal fluid from patients at first presentation. Follow-up ran for well over a decade.
Sixty patients formed the group, and about half worsened in a confirmed way. Each spinal fluid marker alone foresaw that outcome to a degree. Paired, the two markers did better than either one alone. Patients high on both faced a much higher risk than those low on both. Blood levels of one marker did not help.
Catalog record
| CREATOR | Simon Thebault, Seyed-Mohammad Fereshtehnejad, Hailey P Bergman, Gautier Breville, Mohammad Abdoli, Ronald A Booth, Giulia Fadda, Mark S Freedman, Gauruv Bose |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |