Sinomenine Ameliorated Microglial Activation and Neuropathic Pain After Chronic Constriction Injury Via TGF‐β1/ALK5/Smad3 Signalling Pathway
Ling Ling, Min Luo, Haolin Yin, Yunyun Tian, Tao Wang, Bangjian Zhang, Li Yin, Yuehui Zhang, Jiang Bian · 2024
Read Sinomenine Ameliorated Microglial Activation and Neuropathic Pain After Chronic Constriction Injury Via TGF‐β1/ALK5/Smad3 Signalling Pathway by Ling Ling, Min Luo, Haolin Yin, Yunyun Tian, Tao Wang, Bangjian Zhang, Li Yin, Yuehui Zhang, Jiang Bian (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11588427.txt.
Description
Sinomenine (SIN), a bioactive isoquinoline alkaloid extracted from the roots and stems of Sinomenium acutum, is efficacious against various chronic pain conditions. Inhibition of microglial activation at the spinal level contributes to the analgesic effects of SIN. Microglial activation in the spinal dorsal horn is key to sensitising neuropathic pain.
Catalog record
| CREATOR | Ling Ling, Min Luo, Haolin Yin, Yunyun Tian, Tao Wang, Bangjian Zhang, Li Yin, Yuehui Zhang, Jiang Bian |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |