Influenza vaccination in patients with acute heart failure (PANDA II): study protocol for a hospital-based, parallel-group, cluster randomized controlled trial in China

Yiqun Zhang, Rong Liu, Yangyang Zhao, Zhiyan Wang, Chi Wang, Qiang Li, Dorothy Han, Craig S. Anderson, Xin Du, Jianzeng Dong · 2024

Read Influenza vaccination in patients with acute heart failure (PANDA II): study protocol for a hospital-based, parallel-group, cluster randomized controlled trial in China by Yiqun Zhang, Rong Liu, Yangyang Zhao, Zhiyan Wang, Chi Wang, Qiang Li, Dorothy Han, Craig S. Anderson, Xin Du, Jianzeng Dong (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11587674.txt.

Description

Flu shots help many high-risk groups, but proof in acute heart failure is thin, and uptake in China stays low over weak awareness and cost. Zhang and co-authors lay out the plan for PANDA II, a trial that randomizes whole hospitals rather than single patients. Hospitals in one arm offer free flu shots as routine care before discharge, while the other arm keeps the usual limited use.

Each site aims to enroll 50 patients per flu season across three seasons, with follow-up calls at 1, 3, 6, and 12 months after discharge. The main measure is death or return to hospital. The team hopes the design settles whether routine vaccination protects this group.

Catalog record

CREATORYiqun Zhang, Rong Liu, Yangyang Zhao, Zhiyan Wang, Chi Wang, Qiang Li, Dorothy Han, Craig S. Anderson, Xin Du, Jianzeng Dong
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11587674

Browse the full library · About the Tower of Babel