Propylthiouracil-induced vasculitis with alveolar hemorrhage after 31 years of treatment: a case report

Ro’a Khalaf, Deema Mhesin, Hasan Abu Salim, Sari Taha, Waddah Abed · 2024

Read Propylthiouracil-induced vasculitis with alveolar hemorrhage after 31 years of treatment: a case report by Ro’a Khalaf, Deema Mhesin, Hasan Abu Salim, Sari Taha, Waddah Abed (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11587566.txt.

Description

Khalaf and co-authors report a case of vessel inflammation caused by a thyroid drug in a 2024 paper. The drug is known to trigger immune markers, often with no illness. In rare cases it causes true vasculitis, where vessels swell and organs bleed. Their patient was a forty nine year old woman who had taken the drug on and off for thirty one years.

She came in with worsening breathing and general symptoms. Tests found the immune markers, other causes were ruled out, and lung bleeding was present. Stopping the drug and giving steroid treatment resolved her symptoms within a week, with scans and labs improving. The authors urge vigilance over routine lab checks, since onset can come even after decades.

Catalog record

CREATORRo’a Khalaf, Deema Mhesin, Hasan Abu Salim, Sari Taha, Waddah Abed
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE16 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11587566

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