Genetic association of type 2 diabetes mellitus and glycaemic factors with primary tumours of the central nervous system
Yongxue Li, Lihao Lin, Wenhui Zhang, Yan Wang, Yi Guan · 2024
Read Genetic association of type 2 diabetes mellitus and glycaemic factors with primary tumours of the central nervous system by Yongxue Li, Lihao Lin, Wenhui Zhang, Yan Wang, Yi Guan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11587545.txt.
Description
Yongxue Li and co-authors used genetic data in 2024 to test links between type 2 diabetes, blood sugar traits, and tumors of the brain and spine. Diabetes is common and rising, and past studies tied it to these tumors, but cause was unclear. Genetic methods can help sort cause from mere overlap.
The team ran Mendelian randomization and co-localisation checks. They found causal links between diabetes and glioblastoma, a fast-growing brain tumor. Fasting glucose and a long-term sugar marker each linked to spinal cord tumors. A growth factor also linked to spinal cord, pituitary, and other tumors named in the study. Readers get genetic evidence that sugar control and tumor risk may be truly tied. The findings point to new lines for clinic and lab work.
Catalog record
| CREATOR | Yongxue Li, Lihao Lin, Wenhui Zhang, Yan Wang, Yi Guan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |