The effect of expiratory flow limitation on supine persistent hyperinflation in COPD: a prospective observational study

Meera Srinivasan, Hannah Pollard, David G. Chapman, Katrina Tonga, Kieran Patel, Kaj Blokland, David Touma, Cindy Thamrin, Troy Cross, Kim Prisk, Gregory G. King · 2024

Read The effect of expiratory flow limitation on supine persistent hyperinflation in COPD: a prospective observational study by Meera Srinivasan, Hannah Pollard, David G. Chapman, Katrina Tonga, Kieran Patel, Kaj Blokland, David Touma, Cindy Thamrin, Troy Cross, Kim Prisk, Gregory G. King (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11587055.txt.

Description

Meera Srinivasan and co-authors study why lying flat can leave the lungs overfilled in people with chronic lung disease, in work from twenty twenty-four. In this disease, called COPD, airways narrow and trap air. Lying down may worsen that trap and disturb sleep or ease of breath.

The team tested forty-two patients and fourteen healthy controls while seated and lying flat, using sound wave lung measures. Healthy controls gained breathing room when flat, but patients did not. In patients, stiffer lungs and stronger air flow limits while breathing out linked to the flat overfill. Age and low body weight also played a part. The authors tie the effect to airway closure as lung mass shifts with gravity.

Catalog record

CREATORMeera Srinivasan, Hannah Pollard, David G. Chapman, Katrina Tonga, Kieran Patel, Kaj Blokland, David Touma, Cindy Thamrin, Troy Cross, Kim Prisk, Gregory G. King
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11587055

Browse the full library · About the Tower of Babel