Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane
Sho Oasa, Erdinc Sezgin, Yuelong Ma, David A. Horne, Mihajlo D. Radmilović, Tijana Jovanović-Talisman, Rémi Martin-Fardon, Vladana Vukojević, Lars Terenius · 2024
Read Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane by Sho Oasa, Erdinc Sezgin, Yuelong Ma, David A. Horne, Mihajlo D. Radmilović, Tijana Jovanović-Talisman, Rémi Martin-Fardon, Vladana Vukojević, Lars Terenius (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11586411.txt.
Description
Nine authors probe how a drug blocks drink effects on a brain switch in a 2024 cell study. The drug, naltrexone, is a known aid for drink urge, yet its full play past switch block stays dim. Live cell light reads with one-molecule sharpness track the kappa switch in its skin.
Drink at real doses shifts how the switch meets skin fats around it. The drug fights back in two ways, by switch block and by shifts in fat drift and lay. A kin drug in trials lacks that fat play.
Catalog record
| CREATOR | Sho Oasa, Erdinc Sezgin, Yuelong Ma, David A. Horne, Mihajlo D. Radmilović, Tijana Jovanović-Talisman, Rémi Martin-Fardon, Vladana Vukojević, Lars Terenius |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |