PIPETS: a statistically informed, gene-annotation agnostic analysis method to study bacterial termination using 3′-end sequencing
Quinlan Furumo, Michelle M Meyer · 2024
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Description
Quinlan Furumo and Michelle M. Meyer present a new tool for gene data, published in twenty twenty-four. Labs can now read the ends of RNA strands in bacteria at low cost, but no shared method exists to make sense of such data. Their tool, PIPETS, hunts for peaks that mark where RNA ends, without first needing gene maps.
The pair tested PIPETS on data from two kinds of bacteria. It found true end signals in more places, and in more kinds of gene regions, than older tools. Spots that older tools called but PIPETS missed turned out to have very weak data. The tool is free in R, and the authors say non-experts can use it.
Catalog record
| CREATOR | Quinlan Furumo, Michelle M Meyer |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |