Lipid-nanoparticle-induced vacuolization in microglia

Hubert H Kerschbaum, Christopher Gerner, Karin Oberascher, Philip Steiner, Melanie Schürz, Nikolaus Bresgen · 2024

Read Lipid-nanoparticle-induced vacuolization in microglia by Hubert H Kerschbaum, Christopher Gerner, Karin Oberascher, Philip Steiner, Melanie Schürz, Nikolaus Bresgen (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11585578.txt.

Description

Hubert Kerschbaum and a team report in a 2024 study that fat grains can turn brain guard cells into cells full of holes. Such hole filled cells were first seen more than a span of years ago in brains that waste away. A famed brain doctor of that time noted the same cell type, with large fat holes. How the cells take fat waste and turn to that form stayed little known.

The team used two kinds of fat rich grains, each just a trace wide. One kind came from the liver, and one wore a coat of a fat found in ill brains. A fat read showed clear sets of fats in the grains. On film, the grains sped up how the cells drank in fluid. The drink sacs then swelled and formed the hole filled form.

Catalog record

CREATORHubert H Kerschbaum, Christopher Gerner, Karin Oberascher, Philip Steiner, Melanie Schürz, Nikolaus Bresgen
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11585578

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