Altered amino acid levels in young hypopituitarism: impact of NAFLD and insulin resistance
Yuwen Zhang, Jiting Qiu, Shouyue Sun, Xuqian Fang · 2024
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Description
Yuwen Zhang and three colleagues compare amino acid levels in young men whose pituitary gland underworks, in a 2024 study. Such patients often build up fat in the liver and resist insulin, which may shift these building blocks of protein.
The team profiled blood from 133 patients not on growth hormone treatment and 90 matched healthy men. Most amino acids ran higher in the patients. A few, including glutamate and two branched-chain types, tracked closely with insulin resistance. Some also tracked with fatty liver and a metabolic risk score. The authors suggest the shifts stem largely from the liver fat and insulin problems that come with the condition.
Catalog record
| CREATOR | Yuwen Zhang, Jiting Qiu, Shouyue Sun, Xuqian Fang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |