The Impact of Cytomegalovirus Infection on Ulcerative Colitis Relapse: A Multicenter Retrospective Cohort Study
Linmei Xiao, Jingjing Ma, Ruidong Chen, Jie Chen, Qiang Wang, Nana Tang, Xiaojing Zhao, Hongjie Zhang, Chunhua Jiao · 2024
Read The Impact of Cytomegalovirus Infection on Ulcerative Colitis Relapse: A Multicenter Retrospective Cohort Study by Linmei Xiao, Jingjing Ma, Ruidong Chen, Jie Chen, Qiang Wang, Nana Tang, Xiaojing Zhao, Hongjie Zhang, Chunhua Jiao (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11585274.txt.
Description
Linmei Xiao and co-authors asked whether a common virus raises the relapse risk in ulcerative colitis, in a study published in 2024. Cytomegalovirus can inflame the colon in these patients, but its effect on relapse was unclear. The multicenter study followed 298 patients: nineteen with viral colitis, thirty-seven with virus in the blood, and the rest virus-free. Groups were balanced by matching before outcomes were compared.
Over two years, patients with viral colitis relapsed far more often, about eighty-four percent against fifty-two percent of virus-free patients. Five factors independently raised relapse risk, including the viral colitis itself, long disease duration, low albumin, and a stool inflammation marker above a set level. Starting remission with biologic drugs lowered the risk. The authors advise watching viral colitis closely as a relapse warning in colitis care. They also back early biologic use where suitable.
Catalog record
| CREATOR | Linmei Xiao, Jingjing Ma, Ruidong Chen, Jie Chen, Qiang Wang, Nana Tang, Xiaojing Zhao, Hongjie Zhang, Chunhua Jiao |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |