Effects of sodium-glucose cotransporter-2 inhibitors on chronic kidney disease progression: a multi-state survival model

Amarit Tansawet, Panu Looareesuwan, Htun Teza, Sarinya Boongird, Gareth J McKay, John Attia, Oraluck Pattanaprateep, Ammarin Thakkinstian · 2024

Read Effects of sodium-glucose cotransporter-2 inhibitors on chronic kidney disease progression: a multi-state survival model by Amarit Tansawet, Panu Looareesuwan, Htun Teza, Sarinya Boongird, Gareth J McKay, John Attia, Oraluck Pattanaprateep, Ammarin Thakkinstian (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11585174.txt.

Description

Amarit Tansawet and co-authors model in 2024 how a class of diabetes drugs affects the march of chronic kidney disease over ten years. Patients with type two diabetes and stage three kidney disease were split into those who got the drugs and matched peers who did not, in a two to one ratio. A multi state model tracked moves to stage four, stage five, and death.

At ten years, about eighty two percent of the drug group still sat at stage three, against about sixty percent of the matched group. Moves to later stages and death were all less likely on the drugs. The authors say the model gives a fuller picture than single outcome studies of how these drugs slow kidney decline.

Catalog record

CREATORAmarit Tansawet, Panu Looareesuwan, Htun Teza, Sarinya Boongird, Gareth J McKay, John Attia, Oraluck Pattanaprateep, Ammarin Thakkinstian
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE25 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11585174

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