Impact of gut microbiota on metabolic syndrome and its comprising traits: a two-sample mendelian randomization study

Yaodong Zhang, Jinhai Fan · 2024

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Description

Yaodong Zhang and Jinhai Fan test whether gut germs cause metabolic syndrome or merely track with it. Their 2024 study uses gene traits as natural tests, in a method that mimics a trial. Data came from the largest gene studies on hand for each trait. Many hundreds of tests probed links between germ types and the syndrome plus its parts, such as belly fat and blood sugar.

Most links faded under strict checks. Three germ groups kept a small causal push toward belly fat, and all effects were small. The authors read the results as weak proof for a large causal role of gut germs in the syndrome, given the limits of their data.

Catalog record

CREATORYaodong Zhang, Jinhai Fan
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11585155

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