A C2H2-type zinc finger protein TaZFP8-5B negatively regulates disease resistance
Lin Huang, Ruijie Xie, Yanling Hu, Lilin Du, Fang Wang, Xueer Zhao, Yanyan Huang, Xuejiao Chen, Ming Hao, Qiang Xu, Lihua Feng, Bihua Wu, Zhenzhen Wei, Lianquan Zhang, Dengcai Liu · 2024
Read A C2H2-type zinc finger protein TaZFP8-5B negatively regulates disease resistance by Lin Huang, Ruijie Xie, Yanling Hu, Lilin Du, Fang Wang, Xueer Zhao, Yanyan Huang, Xuejiao Chen, Ming Hao, Qiang Xu, Lihua Feng, Bihua Wu, Zhenzhen Wei, Lianquan Zhang, Dengcai Liu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11585113.txt.
Description
Lin Huang and her thirteen co-authors, publishing in 2024, identify a wheat protein that works against the plant's own defenses. Zinc finger proteins help plants manage stress, but their role in disease was murky. The team found one such protein, TaZFP8-5B, whose levels drop when stripe rust fungus attacks wheat. Lab tests showed it carries a built-in off switch for gene activity.
Silencing the protein's gene made wheat more resistant to stripe rust. Forcing extra production made wheat, and even rice, easier for fungi to infect. The protein partners with a calcium-sensing protein, and silencing that partner weakened resistance instead. Together the pair forms a dial that turns immunity down. The authors offer the module as a new lead for breeding or engineering rust-resistant crops, a pressing need since stripe rust destroys harvests worldwide.
Catalog record
| CREATOR | Lin Huang, Ruijie Xie, Yanling Hu, Lilin Du, Fang Wang, Xueer Zhao, Yanyan Huang, Xuejiao Chen, Ming Hao, Qiang Xu, Lihua Feng, Bihua Wu, Zhenzhen Wei, Lianquan Zhang, Dengcai Liu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |