Enhancing antitumor immunity in Lewis lung cancer through plasma-treated medium-induced activation of dendritic cells
Chae Bok Lee, Hei Gwon Choi, Sintayehu Kebede Gurmessa, In-Taek Jang, Naresh Kumar, Zongyou Jiang, Nagendra Kumar Kaushik, Hwa-Jung Kim · 2024
Read Enhancing antitumor immunity in Lewis lung cancer through plasma-treated medium-induced activation of dendritic cells by Chae Bok Lee, Hei Gwon Choi, Sintayehu Kebede Gurmessa, In-Taek Jang, Naresh Kumar, Zongyou Jiang, Nagendra Kumar Kaushik, Hwa-Jung Kim (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11585098.txt.
Description
Chae Bok Lee and co-authors test, in a 2024 study, whether a plasma-treated liquid can wake up immune cells against lung cancer. Cold plasma, an ionized gas, lends the liquid it touches a burst of reactive chemistry. Earlier work showed the treated medium can kill cancer cells, but its power to stir a full immune attack was weak. The team focused on dendritic cells, the sentries that start immune responses.
Treated medium raised reactive oxygen inside Lewis lung cancer cells and pushed them into a death that alerts the immune system. It also lowered a shield protein tumors use to hide. Dendritic cells bathed in the medium grew more active. In mice, injecting those primed cells along with tumor treatment drew more killer T cells into tumors and slowed growth. The authors propose the pairing as a new lung cancer avenue.
Catalog record
| CREATOR | Chae Bok Lee, Hei Gwon Choi, Sintayehu Kebede Gurmessa, In-Taek Jang, Naresh Kumar, Zongyou Jiang, Nagendra Kumar Kaushik, Hwa-Jung Kim |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |