Pine pollen reverses the function of hepatocellular carcinoma by inhibiting α-Enolase mediated PI3K/AKT signaling pathway

Yanhong Luo, Chun Guo, Caixia Ling, Wenjun Yu, Yuanhong Chen, Lihe Jiang, Qiuxiang Luo, Chunfang Wang, Weixin Xu, Turki Talal Turki, Turki Talal Turki, Turki Talal Turki, Turki Talal Turki · 2024

Read Pine pollen reverses the function of hepatocellular carcinoma by inhibiting α-Enolase mediated PI3K/AKT signaling pathway by Yanhong Luo, Chun Guo, Caixia Ling, Wenjun Yu, Yuanhong Chen, Lihe Jiang, Qiuxiang Luo, Chunfang Wang, Weixin Xu, Turki Talal Turki, Turki Talal Turki, Turki Talal Turki, Turki Talal Turki (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11584142.txt.

Description

Yanhong Luo and co-authors present a 2024 study of pine pollen as a brake on liver cancer growth. The team focused on a gene whose altered form is high in these cancer cells. That gene feeds a signal path that helps cells grow, spread, and move.

They built cancer cells that make extra copies of the gene and tested pollen extract on them in dishes. The extract slowed growth, entry into tissue, and movement of those cells. In mice with grafted tumors, pollen shots cut gene levels and tumor weight, and changed liver test values in blood. Growth linked proteins stayed higher in grafts with the extra gene form. The authors say pollen acts through that gene and path.

Catalog record

CREATORYanhong Luo, Chun Guo, Caixia Ling, Wenjun Yu, Yuanhong Chen, Lihe Jiang, Qiuxiang Luo, Chunfang Wang, Weixin Xu, Turki Talal Turki, Turki Talal Turki, Turki Talal Turki, Turki Talal Turki
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE84 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11584142

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